Ten years of iron chelation in a patient with superficial siderosis

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Normal Cerebellar Metabolism in a Patient with Superficial Siderosis

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The traditional role of iron chelation therapy has been to reduce body iron burden via chelation of excess metal from organs and fluids and its excretion via biliary-fecal and/or urinary routes. In their present use for hemosiderosis, chelation regimens might not be suitable for treating disorders of iron maldistribution, as those are characterized by toxic islands of siderosis appearing in a b...

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Deferiprone Superficial siderosis (SS) is a neurodegenerative condition caused by hemosiderin deposition on the surface of the brain, cranial nerves, and spinal cord. SS is an exceptionally rare condition characterized by a triad of hearing loss, ataxia, and myelopathy. The most common etiologies that lead to SS are trauma, previous surgical procedures, dural tears, and tumors of the central ne...

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Superficial siderosis.

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ژورنال

عنوان ژورنال: Neurological Sciences

سال: 2019

ISSN: 1590-1874,1590-3478

DOI: 10.1007/s10072-019-03791-w